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2025.12.18 LABIO Vol.66
🎖️ Introducing a Patented Technology for Delivering High-Concentration Active Ingredients Deep into the Skin 🎖️
Today, we introduce MITᴴᴰ Technology. Developed by LABIO, MITᴴᴰ Technology offers high stability and superior delivery efficiency. With its recent patent registration, the technology has been officially recognized for its proprietary innovation.
🧬 What is MITᴴᴰ Technology?
MITᴴᴰ Technology is LABIO’s proprietary next-generation delivery system based on a multi-lamellar vesicle (MLV) structure. It was developed to deliver active ingredients more stably and efficiently deep into the skin.
This structure is formed by the combination of MEL (Mannosyl Erythritol Lipid) derived from Pseudozyma sp. SY16 and phospholipids. MEL is a LABIO-developed ingredient, a naturally derived multifunctional glycolipid obtained from microorganisms, known for its environmentally friendly properties.
💡 Why the MLV Structure Matters
By combining the biocompatible properties of MEL with the multilayered structure of MLV, the formulation forms multiple stable layers that enable high active ingredient loading, excellent moisturizing performance, and superior delivery efficiency. MLVs feature a flexible, multilamellar structure similar to the skin’s natural lipid layers in the stratum corneum, offering outstanding skin affinity and enabling active ingredients to be delivered deeper and retained longer in the skin. This sophisticated skin-mimicking structure has been clearly confirmed through Cryo-TEM analysis.
📍 Enables high-concentration and high-loading of active ingredients within multi-lamellar vesicle (MLV) liposomes 📍 Deep and long-lasting skin delivery through a multi-infusion mechanism 📍 Enhanced absorption with prolonged efficacy 📍 High-efficiency delivery reaching the dermal layer 📍 Sustainable production using a low-energy cold process 📍 Improved stability of active ingredients within the liposome
💡 Feature 2. Interaction Between MEL and MITᴴᴰ Technology
📍 Enhanced skin affinity for both lipophilic and hydrophilic ingredients 📍 MEL integrates between lecithin layers, maintaining a more robust and stable structure 📍 The tri-acyl groups of MEL act as cross-linkers between MLV layers, facilitating MLV formation and enhancing liposome stability
This concludes our introduction to MITᴴᴰ Technology. MITᴴᴰ Technology is a high-performance delivery platform that combines naturally derived MEL with a multilamellar lipid design, achieving three core values simultaneously: deep penetration, high stability, and long-lasting efficacy. As a skin-friendly yet innovative next-generation delivery technology, it can be applied across a wide range of skincare products. In our next newsletter, we will introduce a new ingredient developed using MITᴴᴰ Technology. Thank you for reading.
That’s all for today’s newsletter! LABIO will continue to explore and research more nature-derived ingredients to innovate skin health. If you’re curious about LABIO’s fermentation technology and diverse ingredients, feel free to reach out to us anytime :)
LABIO cib6@labio.kr
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